Controlled release carbonic anhydrase inhibitor containing pharm

Details Controlled release carbonic anhydrase inhibitor containing pharm Controlled release carbonic anhydrase inhibitor containing pharm

1992-02-20

1998-07-07

Hulina, Amy

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Capsules

424457, 424461, 424462, 424458, 424490, 424494, 424495, 424497, 424499, 424489, A61K 958, A61K 962

Patent

active

057764891

ABSTRACT:
A controlled release pharmaceutical composition in oral dosage unit form comprising a hard or a soft shell capsule containing a filling comprising a therapeutically effective number of active spherical granules comprising an effective amount of at least one carbonic anhydrase inhibitor active medicament, a pharmaceutically acceptable normally solid diluent adapted to form a diffusable matrix for the carbonic anhydrase inhibitor active medicament and an optional pharmaceutically acceptable excipient. A method for the preparation and for the administration of the above defined composition is provided as well.

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Physician's Desk Reference, 43rd Ed., Medical Economics Co. (1989), pp. 1116, 1117, 1137.
Avicel Microcrystalline Cellulose Spheres, FMC Corp. 1985.
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