Controlled release bead, a method of producing the same and...

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Particulate form

Reexamination Certificate

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Details

C424S489000, C424S490000, C424S493000, C424S494000, C424S495000, C424S400000, C424S451000, C424S452000, C424S457000, C424S458000, C424S459000, C424S461000, C424S462000, C424S464000, C424S465000, C424S468000, C514S648000, C514S649000

Reexamination Certificate

active

06911217

ABSTRACT:
A controlled release bead comprises: (i) a core unit of a substantially water-soluble or water-swellable inert material; (ii) a first layer on the core unit of a substantially water-insoluble polymer; (iii) a second layer covering the first layer and containing an active ingredient; and (iv) a third layer of polymer on the second layer effective for controlled release of the active ingredient, wherein the first layer is adapted to control water penetration into the core. A method of producing the controlled release bead is also disclosed.

REFERENCES:
patent: 5645858 (1997-07-01), Kotwal et al.
patent: 6312728 (2001-11-01), Beiman et al.
patent: A2061217 (1982-09-01), None
patent: 7-107450 (1995-01-01), None
patent: 7-275688 (1995-10-01), None
patent: A1-9601621 (1996-01-01), None
patent: A1-9629992 (1996-10-01), None
patent: WO 98/03067 (1998-01-01), None
patent: WO 98/03067 (1998-01-01), None

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