Controlled electrophoresis method

Chemistry: analytical and immunological testing – Involving an insoluble carrier for immobilizing immunochemicals

Reexamination Certificate

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Details

C422S051000, C422S051000, C422S051000, C422S051000, C435S004000, C435S006120, C435S007200, C435S007210, C435S286500, C435S287200, C435S287900, C435S288400, C435S288500, C436S164000, C436S514000, C436S524000, C436S527000, C436S531000, C436S533000, C436S534000, C204S166000, C204S450000, C204S451000, C204S452000, C204S453000, C204S454000, C204S455000, C204S600000, C204S601000, C204S602000, C204S603000, C204S604000, C204S605000

Reexamination Certificate

active

08030092

ABSTRACT:
An electrophoresis apparatus is generally disclosed for sequentially analyzing a single sample or multiple samples having one or more analytes in high or low concentrations. The apparatus comprises a relatively large-bore transport capillary which intersects with a plurality of small-bore separation capillaries and includes a valve system. Analyte concentrators, having antibody-specific (or related affinity) chemistries, are stationed at the respective intersections of the transport capillary and separation capillaries to bind one or more analytes of interest. The apparatus allows the performance of two or more dimensions for the optimal separation of analytes. The apparatus may also include a plurality of valves surrounding each of the analyte concentrators to localize each of the concentrators to improve the binding of one or more analytes of interest.

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