Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Tablets – lozenges – or pills
Reexamination Certificate
2007-05-15
2007-05-15
Zemel, Irina S. (Department: 1711)
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Tablets, lozenges, or pills
C424S078080, C424S458000, C424S459000, C424S461000, C424S464000, C424S470000, C424S497000, C428S357000, C428S402000, C428S403000, C428S407000
Reexamination Certificate
active
10482558
ABSTRACT:
A process for the preparation of a particulate material by a controlled agglomeration method, i.e. a method that enables a controlled growth in particle size. The method is especially suitable for use in the preparation of pharmaceutical compositions containing a therapeutically and/or prophylactically active substance which has a relatively low aqueous solubility and/or which is subject to chemical decomposition. The process comprising i) spraying a first composition comprising a carrier, which has a melting point of about 5° C. or more which is present in the first composition in liquid form, on a second composition comprising a material in solid form, the second composition having a temperature of at the most a temperature corresponding to the melting point of the carrier and/or the carrier composition and ii) mixing or others means of mechanical working the second composition onto which the first composition is sprayed to obtain the particulate material.
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Buur Anders
Elema Michiel Onne
Holm Jannie Egeskov
Holm Per
Møllgaard Birgitte
Corless Peter F.
Edwards Angell Palmer & & Dodge LLP
LifeCycle Pharma A/S
Patton Stephana E.
Zemel Irina S.
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