Controllable pressure cryogenic balloon treatment system and...

Surgery – Instruments – Cyrogenic application

Reexamination Certificate

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Reexamination Certificate

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07060062

ABSTRACT:
Devices, systems, and methods controllably cool blood vessels and other body lumens. The blood vessel will often be treated for atherosclerotic or other diseases by inflating a balloon so as to engage the surrounding luminal wall. Controlled cooling of the balloon effected by a change in phase of a cryogenic fluid within the balloon typically a change from a liquid phase to a gas phase can be provided with a controlled, gradual inflation of the balloon. A single control system can be used for any of a variety of alternative selectable balloon catheters having significantly differing cooling fluid flow characteristics.

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Gage, M.D., Andrew A., et al., “Freezing injury to large blood vessels in dogs,” Surgery, vol. 61, No. 5, May, 1997, pp. 748-754.

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