Control of selective estrogen receptor modulators

Details Control of selective estrogen receptor modulators Control of selective estrogen receptor modulators

2007-08-14

2007-08-14

Hui, San-Ming (Department: 1617)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Cyclopentanohydrophenanthrene ring system doai

C514S182000, C514S650000

Reexamination Certificate

active

09313628

ABSTRACT:
The treatment of an estrogen sensitive condition by the administration of a selective estrogen receptor modulator is improved by additionally administering a progestationally active compound to the recipient. The additional agent can express both progestational and androgenic activity or an androgenically active material can be employed, if desired. Additionally, clomiphene in an array of isomeric ratios (EN:ZU) can be used alone for prevention of osteoporosis, maintenance of a healthful blood lipid profile, and prevention of breast tumors, or to sustain amenorrhea.

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Schane et al. “Fertility in the rhesus monkey following long-term inhibition of ovarian function with danazol” 1978, Fertil. Steril. 29(6), 692-4.

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