Control of secretion of milk

Details Control of secretion of milk Control of secretion of milk

1995-02-28

1996-03-26

Feisee, Lila

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

530344, 530350, 530360, 530832, 530833, 53038824, 530417, 5303871, C07K 1618, C07K 1447

Patent

active

055021638

ABSTRACT:
A protein which inhibits milk secretion by lactating cows and which is present in the second (2A) significant peak when a nominally 10-30 KDa fraction of the whey proteins of the milk is resolved on a "Mono Q" anion exchange column using 10 mM imidazole buffer, pH 7.0 and a sodium chloride elution gradient. Its pI by isoelectric focussing in a gel tube is 4.8 to 5.0.

REFERENCES:
Prentice et al., Biochemical Society Transaction Apr. 24, 1989. p. 122.
Guiding Monoclonal Antibodies: Principles and Practice 1986.
Wilde, C. J. et al., Biochem Biophys Acta (Netherlands) Sep. 15, 1989, 992 (3) pp. 315-319.
Wilde, C. J. et al., O. J. Exp. Physiol. (England) May 1988, 73 (3) pp. 391-397.
Manji, B. et al., J. Dairy Sci., Dec. 1985, 68 (12) pp. 3176-3179.
Hill, A. R. et al., Canadian Institute of Food Science and Technology Journal, Dec. 1986 v. 19 (5) pp. 227-230.
Butler, W. R. et al., J. Dairy Sci. (United States) Mar. 1989, 72 (3) pp. 767-783.

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