Chemistry: molecular biology and microbiology – Process of mutation – cell fusion – or genetic modification – Introduction of a polynucleotide molecule into or...
Reexamination Certificate
2007-09-11
2007-09-11
Mehta, Ashwin (Department: 1638)
Chemistry: molecular biology and microbiology
Process of mutation, cell fusion, or genetic modification
Introduction of a polynucleotide molecule into or...
C435S419000, C435S320100, C435S069100, C435S069700, C800S278000, C536S023600
Reexamination Certificate
active
10924051
ABSTRACT:
Calmodulin-like polypeptides named rgs-CaM are disclosed. cDNAs coding rgs-CaM are also provided. In addition, methods of using rgs-CaM cDNAs and polypeptides for modulating gene expression in plants are also provided.
REFERENCES:
patent: 6972349 (2005-12-01), Vance
patent: WO 01-38512 (2001-05-01), None
Al-Kaff, N., et al., “Transcriptional and post transcriptional plant gene silencing in response to a pathogen,”Science, pp. 2113-2115, vol. 279, (1998).
Anandalakshmi, R., et al., “A viral suppressor of gene silencing in plants,”Proc. Natl. Acad. Sci. USA, 1998, pp. 13079-13084, vol. 95, the National Academy of Sciences.
Anandalakshmi, R., et al., “A Calmodulin-Related Protein That Suppresses Posttranscriptional Gene Silencing in Plants,”Science, 2000, pp. 142-144, vol. 290, American Association for the Advancement of Science.
Baulcombe, D., “Fast forward genetics based on virus-induced gene silencing,”Current Opinion in Plant Biology, 1999, pp. 109-113, vol. 2, No. 2.
Bingham, P., “Cosuppression comes to the animals,”Cell, 1997, pp. 385-387, vol. 90.
Brigneti, G., et al., “Viral pathogenicity determinants are suppressors of transgene silenicng inNicotiana benthamiana,” The EMBO Journal, 1998, pp. 6739-3746, vol. 17, No. 22.
Carrington, J., et al., “Expression of potyviral polyproteins in transgenic plants reveals three proteolytic activities required for complete processing,”The EMBO Journal, 1990, pp. 1347-1353, vol. 9, No. 5.
De La Rosa, A., et al., “Nm23
ucleoside diphosphate kinase: Toward a structural and biochemical understanding of its biological functions,”BioEssays, 1995, pp. 53-62, vol. 17, No. 1, ICSU Press.
Dearolf, C., et al., “Developmental Consequences ofawdb3, a Cell-Autonomous Lethal Mutation ofDrosophilaInduced by Hybrid Dysgenesis,”Developmental Biololgy, 1988, pp. 159-168, vol. 129, Academic Press, Inc.
Depicker, A. and Van Montagu, M., “Post-transcriptional gene silencing in plants,”Curr. Opin. Cell Biol., 1997, pp. 373-382, vol. 9.
Engel, M., et al., “Glyceraldehyde3-phosphate dehydrogenase and NM23-H1
ucleoside diphosphate kinase A. Two old enzymes combine for the Novel Nm23 protein phosphotransferase function,”J. Biol. Chem., 1998, pp. 20058-20065, vol. 273.
Fire, A., et al., Potent and specific genetic interference by double stranded RNA inCaenorhabditis elegens., Nature, 1998, pp. 806-811, vol. 391.
Fire, A., “RNA-triggered gene silencing,”Trends in Genetics, 1999, pp. 358-363, vol. 15, No. 9, Elsevier Ltd.
Grant, S., “Dissecting the mechanisms of post transcriptional gene silencing: Divide and conquer,”Cell, 1999, pp. 303-306, vol. 96.
Howlett, A., et al., “A Novel Function for the nm23-H1 Gene: Overexpression in Human Breast Carcinoma Cells Leads to the Formation of Basement Membrane and Growth Arrest,”Journal of the National Cancer Institute, 1994, pp. 1838-1844, vol. 86, No. 24.
Jones, A., et al., “De novomethylation and co-suppression induced by a cytoplasmically replicating plant RNA virus,”The EMBO Journal, 1998, pp. 6385-6393, vol. 17, No. 21, Oxford University Press.
Kasschau, K., and Carrington, J., “A counterdefensive strategy of plant viruses: Suppression of post transcriptional gene silencing,”Cell, 1998, pp. 461-470, vol. 95.
Kenderdell, J.R., and Carthew, R.W., “Use of dsRNA-mediated genetic interference to demonstrate that frizzled and frizzled 2 act in the wingless pathway,” 1998,Cell, pp. 1017-1026, vol. 95.
Kumagai, M., et al., “cytoplasmic inhibition of carotenoid biosynthesis with virus-derived RNA.”Proc. Natl. Acad. Sci USA, 1995, pp. 1679-1683, vol. 92.
Marathe, R., et al., “RNA viruses as inducers, suppressors and targets of post-transcriptional gene silencing,”Plant Molecular Biology,2000, pp. 295-306, vol. 43, Kluwer Academic Publishers, The Netherlands.
Matzke, M.A., and Matzke, A.J.M., “Homology-dependent gene silencing in transgenic plants: what does it really tell us?,”Trends in Genetics, 1995, pp. 1-3, vol. 11, No. 1, Elsevier Ltd.
Metzlaff, M., et al., “RNA-mediated RNA degradation and chalcone synthase A silencing in Petunia,”Cell, 1997, pp. 845-854, vol. 88.
Montgomery, M.K., and Fire, A., “Double stranded RNA s a mediator in sequence specific genetic silencing and co-suppression,”Trends Genet., 1998, pp. 255-258, vol. 14.
Palauqui,, J., et al., “Frequencies, timing, and Spatial Patterns of Co-suppression of Nitrate Reductase and Nitrite Reductase in Transgenic Tobacco Plants,”Plant Physiol., 1996,pp. 1447-1456, vol. 112.
Palauqui, J., and Vaucheret, H., “Field trial analysis of nitrate reductase co-suppression: a comparative study of 38 combinations of transgene loci,”Plant Molecular Biology, 1995, pp. 149-159, vol. 29, Kluwer Academic Publishers, Belgium.
Postel, E., et al., “Human c-mycTranscription Factor PuF Identified as nm23-H2 Nucleoside Disphosphate Kinase, a Candidate Suppressor of Tumor Metastasis,”Science, 1993, pp. 478-480, vol. 261.
Pruss, G., et al., “Plant Viral Synergism: The Potyviral Genome Encodes a Broad-Range Pathogenicity Enhancer That Transactivates Replication of Heterologous Viruses,”The Plant Cell, 1997, pp. 859-868, vol. 9, American Society of Plant Physiologists.
Ratcliff, F., et al., “A similarity between viral defense and gene silencing in plants,”Science, pp. 1558-1560, vol. 276, (1997).
Ruiz, F., et al., “Homology-dependent gene silencing in Paramecium,”Mol. Biol. Cell, 1998, pp. 931-943, vol. 9.
Ruiz, M., et al., “Initiation and Maintenance of Virus-Induced Gene Silencing,”The Plant Cell, 1998, pp. 937-946, vol. 10, American Society of Plant Physiologists.
Sharp, P., “RNAi and double-strand RNA,”Genes&Dev., 1999, pp. 139-141, vol. 13.
Sharp, P., and Zamore, P., “RNA Interference,”Science, 2000, pp. 2431-2432, vol. 287.
Shi, X., et al., “Mutations in the Region Encoding the Central Domain of Helper Component-Proteinase (HC-Pro) Eliminate Potato Virus X/Potyviral Synergism,”Virology, 1997, pp. 35-42, vol. 231, Academic Press.
Vance, V., “Replication of potato virus X RNA is altered in coinfections with potato virus Y,”Virology, 1991, pp. 486-494, vol. 182, No. 2.
Vance, V., et al., “5′ proximal potyviral sequences mediate potato virus X/potyviral synergistic disease in transgenic tobacco,”Virology, 1995, pp. 583-590, vol. 206, No. 1.
Waterhouse, P., et al., Virus resistance and gene silencing in plants can be induced by simultaneous expression of sense and antisense RNA.,Proc. Natl. Acad. Sci. USA, 1998, pp. 13959-13964, vol. 95.
Wianny, F. and Zernicka-Goetz, M., “Specific interference with gene function by double-stranded RNA in early mouse development,”Nature Cell. Biol., 2000, pp. 70-75, vol. 2.
Rudd, J.J. et al. (1999) “Calcium Signaling in Plants”Cell. Mol. Life Sci. 55: 215-232.
Snedden, W.A. et al. (1999) “Regulation of the γ-Aminobutyrate-Synthesizing Enzyme, Glutamate Decarboxylase, by Calcium-Calmodulin: A Mechanism for Rapid Activation in Response to Stress”Plant Responses to Environmental Stresses: from phytohormones to Genome ReorganizationMarcel Dekker, Inc.: New York, USA, pp. 549-574.
Mehta Ashwin
Myers Bigel & Sibley Sajovec, PA
University of South Carolina
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