Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1986-05-06
1988-01-26
Hollrah, Glennon H.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
549320, 549323, A01N 4308, C07D30712
Patent
active
047217278
ABSTRACT:
Tetrahydrofuranoid acetogenins characteristic of the Annonaceae plant family have been found to have potent pesticidal and feeding deterrent activity against a diverse variety of pests such as mosquito larvae, spider mites, aphids, the Mexican bean beetle, striped cumcumber beetle, blowfly larvae, and nematodes. A new acetogenin called "asimicin" having the following structural formula has been isolated and is typical of the subject class of useful compounds: ##STR1##
REFERENCES:
S. D. Jolad et al., "Uvaricin, a New Antitumor Agent from Uvaria accuminata, (Annonaceae), " J. Org. Chem. 47: 3151-3153, (1982).
S. D. Jolad et al., "Desacetyluvaricin from Uvaria accuminata, Configuration of Uvaricin at C-36," J. Nat. Prod. 48(4): 644-645, (Jul.-Aug. 1985).
T. T. Dabrah et al., "Rollinicin and Isorollinicin, Cytotoxic Acetogenins from Rollinia papilionella," Phytochemistry 23(9): 2013-2016, (1984).
T. T. Dabrah et al., "Rollinone, a New Cytotoxic Acetogenin from Rollinia papilionella," J. Nat. Prod. 47(4): 652-657, (Jul.-Aug. 1984).
D. Cortes et al., "Cherimoline et Dehydrocherimoline, etc" TL, 25, 3199, (1984).
El-Zayat, A. et al., "Goniothalenol: a Novel, etc" TL, 26, 955, (1985).
Rupprecht et al., "Asimicin, a New Cytotoxic, etc." 1986, CA 105: 39355f, 1986.
McLaughlin Jerry L.
Mikolajczak Kenneth L.
Rupprecht James K.
Hollrah Glennon H.
McConnell David G.
Morris Patricia L.
Ribando Curtis P.
Silverstein M. Howard
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