Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1987-10-06
1989-08-08
Hollrah, Glennon H.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
549320, 549323, A01N 4308, C07D30712
Patent
active
048553190
ABSTRACT:
Tetrahydrofuranoid acetogenins characteristic of the Annonaceae plant family have been found to have potent pesticidal and feeding deterrent activity against a diverse variety of pests such as mosquito larvae, spider mites, aphids, the Mexican bean beetle, striped cucumber beetle, blowfly larvae, and nematodes. A new acetogenin called "asimicin" having the following structural formula has been isolated and is typical of the subject class of useful compounds: ##STR1##
REFERENCES:
patent: 4689232 (1987-08-01), Moeschler et al.
Cortes et al, "Cherimoline Et Dihydrocherimoline, etc", TL, 25, 3199 (1984).
Jolad et al. I, "Desacetyluvaricin Fram, etc", J. Nat. Prod., 48, 644 (1985).
Jolad et al. II, "Uvaricin, A New Antitumor, etc", JOC, 47, 3151 (1982).
Dabrah et al. I, "Rollinicin and, etc", Phytochemistry, 23, 2013 (1984).
Dabrah et al. II, "Rollinone, A New Cytotoxic, etc", J. Nat. Prod., 47, 652 (1984).
Thomas R. Hoye et al., "On the Stereochemistry of the Bistetrahydrofuranyl Moiety of Uvaricin: Proton Chemical Shifts Can Play a Crucial Role in Complex Structure Determination", J. Am. Schem. Soc., 109: 4402-4403 (1987).
George R. Pettit et al., "Isolation and Structure of Rolliniastatin 1 from the South American Tree Rollinia mucosa", Can. J. Chem., 65: 1433-1435 (1987).
McLaughlin Jerry L.
Mikolajczak Kenneth L.
Rupprecht James K.
Brokke Mervin E.
Hollrah Glennon H.
Morris Patricia L.
Ribando Curtis P.
Silverstein M. Howard
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