Drug – bio-affecting and body treating compositions – Whole live micro-organism – cell – or virus containing – Genetically modified micro-organism – cell – or virus
Patent
1987-07-20
1988-11-01
Schain, Howard E.
Drug, bio-affecting and body treating compositions
Whole live micro-organism, cell, or virus containing
Genetically modified micro-organism, cell, or virus
424 93, 435832, A61K 3907, A01N 6300
Patent
active
047819227
ABSTRACT:
A method of controlling nematodes in host animals comprising contacting a bacterial extract capable of inhibiting the egg hatching ability of a nematode with said animal and/or its environment. The preferred bacterium for producing the toxin is Bacillus sphaericus.
REFERENCES:
patent: 4000258 (1976-12-01), Shieh et al.
patent: 4666714 (1987-05-01), Cayrol
patent: 4713241 (1987-12-01), Wakisaka et al.
Leon W. Bone et al., "Trichostrongylus colubriformis: Larvicidal Activity of Toxic Extracts from Bacillus sphaerics (Strain 1593) Spores," Exptl. Parasitol. 64: 514-516 (1987).
H. Ciordia et al., "A Preliminary Report on the Effects of Bacillus thuringiensis var. Thuringiensis Berliner on the Development of the Free-Living Stages of Some Cattle Nematodes," Abstr. #86, J. Parasitol. 47: 41 (Aug. 1961.).
K. P. Bottjer et al., "Nematoda: Susceptibility of the Egg to Bacillus thuringiensis Toxins," Exptl. Parasitol. 60: 239-244 (1985).
R. Tinelli et al., "Isolement d'une Fraction de Spore de Bacillus sphaericus Toxique pour les Larves d'Anopheles," C. R. Acad. Sc. Paris, Series D 291: 537-539 (Oct. 13, 1980).
R. Tinelli et al., "Larvicidal Toxin from Bacillus sphaericus Spores," FEBS Letters 142(1): 155-158 (Jun. 1982).
Ribando Curtis P.
Schain Howard E.
Silverstein M. Howard
The United States of America as represented by the Secretary of
LandOfFree
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