Control of mastitis and compositions therefor

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...

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424319, A61K 31045, A61K 31195

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active

041996020

ABSTRACT:
Neutral to mildly acidic externally-applied mastitis control agents based upon antimicrobial nitroalkanols (e.g. 2-bromo-2-nitropropane-1,3-diol) can be made more effective against Pseudomonas aeruginosa through "potentiation" with an aminocarboxylic-type chelating agent. The chelating agent is believed to improve cell-wall permeability, even at a pH well below 7.

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patent: 2904468 (1959-09-01), Davis et al.
patent: 3558788 (1971-01-01), Clark et al.
patent: 3629464 (1971-12-01), Nosler et al.
Noesler et al.-Chem. Abst. vol. 71 (1969) p. 49,242k.
Hague et al.-Antimicrobial Agents & Chemotherapy, vol. 6 (Aug. 1974) p. 200.

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