Control of aberrant expression vector accumulation during fermen

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

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435 911, 4351723, 4353171, 4353201, C12P 2102, C12P 1934, C12N 1570, C12N 121

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058244964

ABSTRACT:
The present invention provides a method for preventing the accumulation of aberrant expression vectors during fermentation processes which rely on the expression of an expression vector coded gene for production of a polypeptide product of interest. Antibiotics are added at approximately the time at which product expression begins.

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