Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1995-08-10
1998-10-20
Degen, Nancy
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
435 911, 4351723, 4353171, 4353201, C12P 2102, C12P 1934, C12N 1570, C12N 121
Patent
active
058244964
ABSTRACT:
The present invention provides a method for preventing the accumulation of aberrant expression vectors during fermentation processes which rely on the expression of an expression vector coded gene for production of a polypeptide product of interest. Antibiotics are added at approximately the time at which product expression begins.
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Boone David E.
Cantrell Paul R.
Degen Nancy
Eli Lilly and Company
Gaylo Paul J.
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