Control for blood gas analyzers and hemoglobin analysis

Chemistry: analytical and immunological testing – Composition for standardization – calibration – simulation,... – Protein or peptide standard or control

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436 16, 436 8, 436 11, G01N 3100

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active

047118520

ABSTRACT:
A blood gas-hemoglobin analysis control which simulates whole human blood characteristics comprising a buffered suspension medium containing erythrocytes which have been stabilized with an imidoester protein cross-linking agent while being contacted with a gas consisting of pure oxygen or pure carbon monoxide.

REFERENCES:
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patent: 4485174 (1984-11-01), Chiang et al.
patent: 4521518 (1985-06-01), Carter et al.
Niehaus, W. G., et al, "Cross-Linking of Erythrocyte Membranes with Dimethyl Adipimidate," Biochim. Biophys. Acta 196:170-175 (1970).
Lubin, B. H., et al, "Dimethyl Adipimidate: A New Antisickling Agent", Proc. Nat. Acad. Sci U.S.A., vol. 72, No. 1, pp. 43-46, Jan. 1975.
Waterman, M. R., et al, "Antisickling Nature of Dimethyl Adipimidate, " Biochem. Biophys. Res. Comm., vol. 63:No. 3, 580-587 (1975).
Krinsky, N. I., et al, "Retention of K.sup.+ Gradients in Imidoester Cross-Linded Erythrocyte Membranes,: Arch. Biochem. Biophys., 160 350-352 (1974).

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