Control compositions for determination of molecular cytogenetic

Details Control compositions for determination of molecular cytogenetic Control compositions for determination of molecular cytogenetic

1995-10-05

1997-12-16

Horlick, Kenneth R.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

4352402, 43524025, C12Q 168

Patent

active

056983980

ABSTRACT:
Quality control compositions suitable as sample specimens to measure performance of DNA probe tests which determine cytogenetic abnormalities, such as chromosome copy number, of cells in a tissue sample are disclosed. The control compositions comprise a suspension of fixed cells having an artificial concentration of cells exhibiting chromosome specific aneuploidy in one or more specific chromosomes.

REFERENCES:
patent: 5059518 (1991-10-01), Kortright et al.
patent: 5409826 (1995-04-01), Maples et al.
van Dekken et al., Cancer 66, 491-497 (1990).
Klinger et al., Am. J. Hum. Genet. 51, 55-65 (1992-Jul.).
Paxton et al., Int. Soc. Analy. Cytol., 16 (Mar. 1993).

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