Contrast enhancing solution for use in confocal microscopy

Details Contrast enhancing solution for use in confocal microscopy Contrast enhancing solution for use in confocal microscopy

2006-10-31

2006-10-31

Helms, Larry R. (Department: 1643)

Drug, bio-affecting and body treating compositions

In vivo diagnosis or in vivo testing

Reexamination Certificate

active

07128894

ABSTRACT:
A method of optically detecting a tumor during surgery. The method includes imaging at least one test point defined on the tumor using a first optical imaging system to provide a first tumor image. The method further includes excising a first predetermined layer of the tumor for forming an in-vivo defect area. A predetermined contrast enhancing solution is disposed on the in-vivo defect area, which is adapted to interact with at least one cell anomaly, such as basal cell carcinoma, located on the in-vivo defect area for optically enhancing the cell anomaly. Thereafter the defect area can be optically imaged to provide a clear and bright representation of the cell anomaly to aid a surgeon while surgically removing the cell anomaly.

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