Contrast agents for ultrasound imaging

Details Contrast agents for ultrasound imaging Contrast agents for ultrasound imaging

1991-12-04

1993-03-23

Hollrah, Glennon H.

Drug, bio-affecting and body treating compositions

In vivo diagnosis or in vivo testing

Magnetic imaging agent

514 12, 514 13, 514 21, 514558, 12866001, 12866202, 530363, 530427, 424 2, A61K 4900, A61B 812

Patent

active

051961830

ABSTRACT:
Particles having an average diameter of less than about 12 microns comprising fatty acid cores encapsulated with human serum albumin and methods for their preparation are disclosed. These materials are useful as contrast agents in ultrasonic imaging, having scattering intensities that are equivalent to or greater than those obtain from dispersed microbubbles but being much more stable, both in storage and when used in vivo, than are contrast agents based on dispersed microbubbles.

REFERENCES:
patent: 4572203 (1986-02-01), Feinstein
patent: 4718433 (1988-01-01), Feinstein
patent: 4774958 (1988-10-01), Feinstein
patent: 4832941 (1989-05-01), Berwing et al.
patent: 4844882 (1989-07-01), Widder et al.
patent: 4957656 (1990-09-01), Cerny et al.

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