Contrast agents

Organic compounds -- part of the class 532-570 series – Organic compounds – Amino nitrogen containing

Reexamination Certificate

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C424S009452

Reexamination Certificate

active

08067637

ABSTRACT:
The present invention relates to a class of compounds and to diagnostic compositions containing such compounds where the compounds are iodine containing compounds. More specifically the iodine containing compounds are chemical compounds containing a hydrophilic aliphatic central moiety allowing for the arrangement of three iodinated phenyl groups bound thereto. The invention also relates to the use of such diagnostic compositions as contrast agents in diagnostic imaging and in particular in X-ray imaging and to contrast media containing such compounds.

REFERENCES:
patent: 3781338 (1973-12-01), Wiegert
patent: 5851511 (1998-12-01), Le Lem et al.
patent: 95/01966 (1995-01-01), None
Felder E., et.al. Farmaco, Edizione Scientifica, vol. 28, No. 11, 1973 pp. 912-924.
Weichert, J.P., et.al. “Potential tumor or organ-imaging agents. 27. polyiodinated 1,3-disubstituted and 1,2,3-trisubstituted triacylglycerols” Journal of Medicinal Chemistry, vol. 29, No. 12, 1986, pp. 2457-2465.
PCT/NO2007/000045 Int'l Search Report/Written Opinion dated Jun. 2007.

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