Contrast agents

Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing

Reexamination Certificate

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Details

C424S001110, C424S001650, C424S001810, C424S001850, C424S001890, C534S014000

Reexamination Certificate

active

07413727

ABSTRACT:
The invention provides a composition of matter of the formula (I): V-L-R, where V is a vector moiety having affinity for an angiogenesis-related endothelias cell receptor, L is a linker moiety or a bond and R is a detectable moiety, characterised in that V is a non-peptidic organic group, or V is peptidic and R is a macromolecular or particulate species providing a multiplicity of labels detectable in in vivo imaging.

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patent: 195 22 774 (1997-01-01), None
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patent: 96 23524 (1996-08-01), None
Chemical Abstracts, 126;26, Jun. 30, 1997, abstract No. 340590, Nitschke, R. et al.; “A Modified Confocal Laser Scanning Microscope Allows Fast Ultraviolet Ratio Imaging of Intracellular Ca2+ activity using Fura-2”, XP002074474.
Chemical Abstracts, 121;17, Oct. 24, 1994, abstract No. 199859, Condrau, Marc A. et al.; “Time-resolved Flow Cytometry for the Measurement of Instrument Design and Experimental Results”, XP002074475.

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