Contrast agent for NMR scanning

Details Contrast agent for NMR scanning Contrast agent for NMR scanning

1986-07-11

1989-11-14

Rosenbaum, C. Fred

Surgery

Truss

Pad

424 9, 534 15, A61K 4900

Patent

active

048800074

ABSTRACT:
Complexes formed between (a) an amino di- or poly-phosphonate in which phosphonate groups comprise separate carbon atoms and (b) a paramagnetic metal ion such as Gd.sup.3+, have calcified tissue seeking properties which make them useful as contrast agents for investigating bone metabolism by NMR scanning. Two preferred poly-phosphonates are ethylenediamine tetramethylphosphonate and meta-xylene-diamine tetramethylphosphonate.

REFERENCES:
patent: 4639364 (1987-01-01), Hoey
patent: 4647447 (1987-03-01), Gries et al.
patent: 4749560 (1988-06-01), Elgavish

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