Contraceptive regimen

Details Contraceptive regimen Contraceptive regimen

1994-01-14

1995-05-23

Henley, III, Raymond

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Cyclopentanohydrophenanthrene ring system doai

514170, 514179, 514843, A61K 3156

Patent

active

054182280

ABSTRACT:
A contraceptive method and regimen utilizing an initially greater amount of progestogen, which gradually tapers over the period in which the contraceptive is administered. The regimen includes a multiphasic combination and contraceptive kit containing at least 21 daily sequential dosage units divided into 3 phases. The first phase contains 6-8 dosage units, each containing a progestogen at a dosage equivalent in progestogenic activity to 75-150 .mu.g desogestrel and an estrogen at a dosage equivalent in estrogenic activity to 20-25 .mu.g ethinyl estradiol. The second phase contains 6-8 dosage units, each containing less progestogen than in the previous dosage units, but still having progestogen equivalent to 75-125 .mu.g desogestrel and an estrogen equivalent to 20 .mu.g ethinyl estradiol. The third phase contains 6-8 dosage units, each containing less progestogen than in the previous dosage units, but still containing a progestogen equivalent to 75-100 g desogestrel and an estrogen equivalent to 20 .mu.g ethinyl estradiol. The kit may also include another phase of 4 to 7 dosage units having no contraceptive steroid.

REFERENCES:
patent: 4530839 (1985-07-01), Pasquale
patent: 4962098 (1990-10-01), Boissenneault

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