Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...
Patent
1982-01-20
1983-12-27
Helfin, Bernard
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Recombinant or stably-transformed bacterium encoding one or...
560 34, 424304, 424251, 424267, 424263, 424270, 424272, 424278, 424285, 546173, A61K 31155, A61K 31245
Patent
active
044230699
ABSTRACT:
Contraceptive method comprises maintaining in the genital tract of a mammal an ester of 4-guanidinobenzoic acid and certain substituted phenols in a concentration effective to inhibit the fertilization of ova. In addition to effectively inhibiting the enzymes necessary for conception, the compounds used in the method of the invention are advantageous in possessing low toxicity. Further, the phenolic materials which may be liberated on hydrolysis of the 4-guanidinobenzoates in the genital tract of the animal are low in toxic, caustic or irritating properties, so that the contraceptive compositions are suitable for long-term use without adverse side-effects.
REFERENCES:
patent: 4224342 (1980-09-01), Fujii et al.
patent: 4283418 (1981-08-01), Fujii et al.
Bauer Ludwig
Kaminski Joanne M.
Zaneveld Lourens
Helfin Bernard
University of Illinois Foundation
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