Compositions – Preservative agents – Anti-corrosion
Patent
1988-09-14
1990-09-18
Lovering, Richard D.
Compositions
Preservative agents
Anti-corrosion
12866202, 424 9, B01J 1302, A61K 4900
Patent
active
049576569
ABSTRACT:
An ultrasonic imaging agent is produced by a continuous sonication processing of an aqueous solution of heat-denaturable biocompatible protein. The solution is carefully preheated to a temperature of incipient protein denaturation without forming insolubilized protein. A gaseous fluid, preferably air, is added to the solution. In the sonication, the air-containing solution is foamed, increasing the formation and concentration of microbubbles, and the solution is further heated to insolubilize a portion of the protein, thereby encapsulating the microbubbles and forming particulate microspheres.
REFERENCES:
patent: 4276885 (1981-07-01), Tickner et al.
patent: 4466442 (1984-08-01), Hilmann et al.
patent: 4572203 (1986-02-01), Feinstein
patent: 4718433 (1988-01-01), Feinstein
patent: 4774958 (1988-10-01), Feinstein
patent: 4832941 (1989-05-01), Berwing et al.
patent: 4844882 (1989-07-01), Widder et al.
Keller, Feinstein, and Watson, American Heart Journal, vol. 114, No. 3, Sep. 1987, pp. 570-575.
Tickner and Rasor, National Technical Information Service Report, HR 62917-1A, Mar. 13, 1986, pp. 34-40.
Feinstein et al., JACC, vol. 3, No. 1, Jan. 1984, pp. 14-20.
Cerny David
Mills Gary J.
Westkaemper Peter J.
Lovering Richard D.
Metzmaier Daniel S.
Molecular Biosystems, Inc.
LandOfFree
Continuous sonication method for preparing protein encapsulated does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Continuous sonication method for preparing protein encapsulated , we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Continuous sonication method for preparing protein encapsulated will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1571197