Prosthesis (i.e. – artificial body members) – parts thereof – or ai – Implantable prosthesis
Patent
1994-02-15
2000-01-11
Isabella, David
Prosthesis (i.e., artificial body members), parts thereof, or ai
Implantable prosthesis
623 16, 623 66, A61F 202, A61F 228
Patent
active
06013853&
ABSTRACT:
Biodegradable, porous, polymeric implant material provides substantially continuous release of bioactive agent during in vivo use. Bioactive agent is initially released in amounts that are less than degradation rate of polymer, thereby promoting migration of cells into material. Later larger amounts of bioactive agent is released, thereby promoting differentiation of cells. Method of making material includes step of applying vacuum to form pores. Implant material may be adapted for one phase implant (e.g., for bone or cartilage) or for two phase layered implant (e.g., for cartilage layer on top of bone layer).
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Athanasiou Kyriacos A
Boyan Barbara D
Isabella David
The University of Texas System
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