Continuous release pharmaceutical compositions formed by freeze

Details Continuous release pharmaceutical compositions formed by freeze Continuous release pharmaceutical compositions formed by freeze

1986-05-12

1991-04-02

Page, Thurman

Drug, bio-affecting and body treating compositions

Solid synthetic organic polymer as designated organic active...

Polymer from ethylenic monomers only

424423, 424499, 424468, A61K 3174, A61K 950

Patent

active

050046020

ABSTRACT:
Pharmaceutical compositions, comprising a polylactide and a pharmacologically active, acid stable polypeptide, which when placed in an aqueous physiological equipment release the polypeptide at an approximately constant rate in an essentially monophasic manner, with a minimal, or no induction period prior to the release; polylactides suitable for use in said compositions; and a method for the manufacture of such polylactides.

REFERENCES:
patent: 3773919 (1973-11-01), Boswell et al.
patent: 3887699 (1975-06-01), Yolles
patent: 3976071 (1976-08-01), Sadek
patent: 4767628 (1988-08-01), Hutchinson
Theory and Practice of Industrial Pharmacy, 2nd. Ed., Lea & Febiger, Phila., 1976, pp. 521-524, 599-600.
Progress in Contraceptive Delivery Systems-Ed-MTP Press Ltd., vol. 1-Skeins at al., pp. 3-14.

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