Continuous release pharmaceutical compositions

Details Continuous release pharmaceutical compositions Continuous release pharmaceutical compositions

1987-06-29

1988-08-30

Brown, J. R.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

514 12, 514 13, 514 14, 514 15, A61K 926, A61K 932

Patent

active

047676280

ABSTRACT:
Pharmaceutical compositions, comprising a polylactide and a pharmacologically active, acid stable polypeptide, which when placed in an aqueous physiological environment release the polypeptide at an approximately constant rate in an essentially monophasic manner, with a minimal, or no induction period prior to the release; polylactides suitable for use in said compositions; and a method for the manufacture of such polylactides.

REFERENCES:
patent: 3773919 (1973-11-01), Boswell et al.
patent: 3887699 (1975-06-01), Yolles
patent: 3976071 (1976-08-01), Sadek
patent: 4331652 (1982-05-01), Ludwig et al.
patent: 4333919 (1982-06-01), Kleber et al.

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