Continuous release formulations

Details Continuous release formulations Continuous release formulations

1985-03-27

1990-07-17

Waddell, Frederick E.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

424 78, 424 80, 424422, 424499, A61K 3174, A61K 3179, A61F 200

Patent

active

049420356

ABSTRACT:
Pharmaceutical compositions comprising a pharmacologically active polypeptide and a pharmacologically or veterinarily acceptable amphipathic, non-cross-linked linear, branched or graft block copolymer, which has a minimum weight average molecular weight of 5,000, in which the hydrophobic component is biodegradable and the hydrophilic component may or may not be biodegradable, the composition being capable of absorbing water to form a hydrogel when placed in an aqueous, physiological-type environment; copolymers suitable for use in said compositions; and method for the manufacture of such copolymers.

REFERENCES:
Das, "Controlled Release Technology" John Wiley and Sons, Inc. 1983 pp. 9-10.

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