Continuous processes for the hydrolysis of cyanopyridines under

Details Continuous processes for the hydrolysis of cyanopyridines under Continuous processes for the hydrolysis of cyanopyridines under

1997-02-07

1998-05-26

Ivy, C. Warren

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546317, 546286, C07D21380, C07D21356

Patent

active

057567506

ABSTRACT:
Described are preferred processes for hydrolyzing substituted and unsubstituted cyanopyridines in the presence of a base and under substantially adiabatic conditions to produce pyridine substituted amides and/or pyridine substituted carboxylic acids. Preferred processes can be conducted in a variety of continuous reactors including cascades of reaction vessels, loop reactors or flow tube reactors. More preferred are the efficient and advantageous preparations of nicotinamide and niacin, which serve as important members of the B-vitamin complex.

REFERENCES:
patent: 2471518 (1949-05-01), Duesel
patent: 4314064 (1982-02-01), Beschke et al.
patent: 4959478 (1990-09-01), Moller
patent: 5395758 (1995-03-01), Takashima et al.
Krewson, C.F. and Couch, J.F., "The Hydrolysis of Nicotinonitrile by Ammonia", J. Am. Chem. Soc., vol. 65, pp. 2256-7 (1943).
Suvorov, B.V., Kagarlitskii, A.D., Suslova, N.V., Efremov, Yu. G. and Erzhanov, M.K., "Continuous Method For Hydrolysis of 3-Cyanopyridine to Nicotinamide and Nicotinic Acid", J. App. Chem. of the USSR, (English Translation: 45:2716-2718(1972)).

Affiliated with

Also associated with

Rating

Continuous processes for the hydrolysis of cyanopyridines under does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Continuous processes for the hydrolysis of cyanopyridines under , we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Continuous processes for the hydrolysis of cyanopyridines under will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1962153