Continuous process for preparing indolenine compounds

Details Continuous process for preparing indolenine compounds Continuous process for preparing indolenine compounds

1991-07-03

1994-02-22

Ramsuer, Robert W.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

548411, 548491, C07D20908

Patent

active

052888770

ABSTRACT:
Described is a continuous process for preparing indolenine compounds which comprises charging continuously and simultaneously to a reactor containing an acetic acid reaction medium (1) substituted phenylhydrazine and (2) unsymmetrical ketone from separate sources, continuously discharging from the reactor indolenine product in acetic acid solution, separating acetic acid from the indolenine product, recycling separated acetic acid to the reactor, neutralizing residual acetic acid remaining in the indolenine product with aqueous inorganic alkaline reagent, and separating from the indolenine product an aqueous solution of salts resulting from the preparation and neutralization of the indolenine product.

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