Continuous preparation of solid pharmaceutical forms

Details Continuous preparation of solid pharmaceutical forms Continuous preparation of solid pharmaceutical forms

1989-08-25

1991-12-17

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

424400, 424464, 424465, 424468, A61K 944, A61K 920

Patent

active

050733796

ABSTRACT:
A mixture of one or more pharmaceutical active compounds and one or more thermoplastic polymers is tabletted by a process in which the mixture is extruded and the still moldable extrudate is pressed to give tablets, between two belts, or a belt and a roller, which make contact in parts, rotate in opposite directions and run parallel along the contact zone, the shape-imparting indentations, which may be present in complementary pairs, being located in both or in only one of the revolving shape-imparting elements.

REFERENCES:
patent: 2829756 (1958-04-01), Gercke et al.
patent: 3089818 (1963-05-01), Stone
patent: 3432592 (1969-03-01), Speiser
patent: 4072551 (1978-02-01), Dabal et al.
patent: 4349531 (1982-09-01), Mlodozeniec et al.
patent: 4631284 (1986-12-01), Salpekar et al.
patent: 4661521 (1987-04-01), Salpekar et al.

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