Continuous microsphere process

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Particulate form

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424486, 424497, 424425, A61K 914

Patent

active

059451262

ABSTRACT:
A continuous process for producing microspheres wherein small particle sizes can be obtained without the problem of foaming. A drug and polymer containing dispersed phase is continuously introduced into a high intensity emulsification vessel along with a continuous phase. An emulsion of the dispersed phase is formed in the continuous phase by high intensity mixing effective to quickly solidify the dispersed phase polymer without having to take steps to address foaming.

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