Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acids and salts thereof
Patent
1997-06-13
1999-12-07
Burn, Brian M.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carboxylic acids and salts thereof
562581, C07C 5142, C07C38100
Patent
active
059986646
ABSTRACT:
A continuous process for the preparation of 2-hydroxy-4-methylthiobutanoic acid which includes introducing sulfuric acid into a first reactor including a continuous stirred tank reactor and introducing 2-hydroxy-4-methylthiobutanenitrile into the first reactor. 2-hydroxy-4-methylthiobutanenitrile is continually hydrolyzed within the first reactor to produce an intermediate aqueous hydrolysis solution containing 2-hydroxy-4-methylthiobutanamide. The intermediate aqueous hydrolysis solution is continuously introduced into a plug flow reactor. 2-hydroxy-4-methylthiobutanamide is continually hydrolyzed within the plug flow reactor to produce an aqueous hydrolyzate product solution containing 2-hydroxy-4-methylthiobutanoic acid. 2-hydroxy-4-methylthiobutanoic acid is recovered from the aqueous hydrolyzate product solution.
REFERENCES:
patent: 2485236 (1949-10-01), Gresham et al.
patent: 2542768 (1951-02-01), Gresham et al.
patent: 2557920 (1951-06-01), White et al.
patent: 2564105 (1951-08-01), Gresham et al.
patent: 2642459 (1953-06-01), White et al.
patent: 2688038 (1954-08-01), Merner
patent: 2745745 (1956-05-01), Blake et al.
patent: 2938053 (1960-05-01), Blake et al.
patent: 2946818 (1960-07-01), Anagnostopoulos
patent: 3773927 (1973-11-01), Cummins
patent: 3968152 (1976-07-01), Sze et al.
patent: 4233235 (1980-11-01), Camden et al.
patent: 4310690 (1982-01-01), Cummins
patent: 4311803 (1982-01-01), Smith et al.
patent: 4524077 (1985-06-01), Ruest et al.
patent: 4677224 (1987-06-01), Commeyras et al.
patent: 4912257 (1990-03-01), Hernandez et al.
patent: 5068383 (1991-11-01), Bourgoin et al.
patent: 5244590 (1993-09-01), Chung et al.
patent: 5250611 (1993-10-01), Baumgartner et al.
patent: 5420304 (1995-05-01), Verser et al.
Kenneth Denbigh, "Chemical Reactor Theory," Cambridge at the University Press, 1965, Chapters 2-4, pp. 38-124.
A. Cholette & J. Blanchet, "Optimum . . . Conditions", The Can. J. of Chem. Eng., pp. 192-198, Oct. 1961.
Cholette et al., "Performance of Flow Reactors . . . Mixing", The Can. J. of Chem. Eng., pp. 1-18, Feb. 1960.
Trambouze et al., A.I.Ch.E. Journal, "Continuous Stirred Tank Reactors," Sep. 1959, vol. 5, pp. 384-390.
Blackburn Thomas F.
Hsu Yung C.
Kranz Allen H.
Pellegrin Paul F.
Willock James M.
Burn Brian M.
Keys Rosalynd
Novus International, Inc.
LandOfFree
Continuous hydrolysis process for the preparation of 2-hydroxy-4 does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Continuous hydrolysis process for the preparation of 2-hydroxy-4, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Continuous hydrolysis process for the preparation of 2-hydroxy-4 will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-825758