Chemistry: molecular biology and microbiology – Spore forming or isolating process
Patent
1985-07-01
1989-02-28
Tarcza, John Edward
Chemistry: molecular biology and microbiology
Spore forming or isolating process
435 6, 435 29, 435 32, 435948, 935 71, C12N 500, C12Q 168, C12Q 102, C12Q 118
Patent
active
048085324
ABSTRACT:
Substantially genetically stable continuous human cell lines derived from normal human mammary epithelial cells (HMEC) and processes for making and using the same. In a preferred embodiment, the cell lines are derived by treating normal human mammary epithelial tissue with a chemical carcinogen such as benzo[a]pyrene. The novel cell lines serve as useful substrates for elucidating the potential effects of a number of toxins, carcinogens and mutagens as well as of the addition of exogenous genetic material. The autogenic parent cells from which the cell lines are derived serve as convenient control samples for testing. The cell lines are not neoplastically transformed, although they have acquired several properties which distinguish them from their normal progenitors.
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Carnahan L. E.
Gaither Roger S.
Hightower Judson R.
Tarcza John Edward
The United States of America as represented by the United States
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