Continuous flow tissue homogenizer

Solid material comminution or disintegration – Apparatus – Cooperating comminuting surfaces

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241 2, 2411691, 241258, 241259, B02C 1900

Patent

active

043078460

ABSTRACT:
A continuous flow tissue homogenizer is disclosed and includes a generally tubular container (12) with an inner surface (60) defining a tissue homogenization chamber (19). One end of the container has an inlet (46) for the introduction of non-homogenized tissue in solution and the other end of the container has an outlet (36) for the discharge of homogenate. A pestle member (38) is disposed within the homogenization chamber and mounted to a shaft (40) for rotatably driving the pestle member. The pestle member has an outer surface (62) that is spaced apart from the inner surface of the container to provide a tissue disruption zone (64) therebetween. The pestle member divides the homogenization chamber into first portion (54) and second portion (56). A plurality of grooves (68) are circumferentially spaced about the outer surface of the pestle member and open into the first chamber portion to channel the tissue solution into the tissue disruption zone of the apparatus.

REFERENCES:
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patent: 1021950 (1912-04-01), Shepard
patent: 2749053 (1956-06-01), Rieth
patent: 2886253 (1959-05-01), Skibicki et al.
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patent: 3587982 (1971-06-01), Campbell
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patent: 3750964 (1973-08-01), Cohen et al.
patent: 3912179 (1975-10-01), Hartig, Jr. et al.

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