Continuous flow analyzing method and apparatus

Details Continuous flow analyzing method and apparatus Continuous flow analyzing method and apparatus

1995-04-28

1997-04-29

Soderquist, Arlen

Chemistry: analytical and immunological testing

Automated chemical analysis

Condition or time responsive

436 52, 436 55, 436 73, 436 81, 436166, 436175, 436177, 436178, 422 62, 422 81, 422 82, 422108, G01N 3508

Patent

active

056248466

ABSTRACT:
A continuous flow analyzing method and an apparatus for carrying out the analyzing method wherein a sample is injected in a continuously flowing carrier and the sample is introduced into a detector by the carrier to thereby perform a quantitative analysis contained in the sample. In the method the sample to be analyzed is filled into a sample introduction switchover valve (SISV); a portion of the sample from the SISV is injected into the carrier and an analysis of this sample is conducted to obtain a detection peak for the analyzed sample. These steps are repeated and the sample is continuously analyzed by, in the case where a detection peak obtained in the detector is under an optimum analysis range, increasing an injection amount of the sample, and in the case where the detection peak obtained in the detector is over the optimum range, decreasing the injection amount of the sample. Adjustment of the detection peak is repeated until the detection peak reaches the optimum analysis range. Since it is possible to precisely control the injection amount of the sample, it is possible to conduct a high precision quantitative analysis. It is possible to apply the method to a sample having a concentration as low as about 1 ng/ml up to a concentration as high as about 1,000 .mu.g/m with the same apparatus system by feeding the results obtained in a detector back to a sample feed system.

REFERENCES:
patent: H1310 (1994-05-01), Peterson et al.
patent: 4080171 (1978-03-01), Sano et al.
patent: 5178771 (1993-01-01), Hayashibe et al.
patent: 5387524 (1995-02-01), Hayashibe et al.
F. Malamas et al. Anal. Chim. Acta 1984, 160, 1-10.
J. L. Burguera et al. Anal. Chim. Acta 1989, 234, 253-257.
M. Sollacaro et al. J. Auto. Chem. 1992, 14, 101-105.
B. Welz et al. Anal. Chim. Acta 1992, 261, 477-487.
D.J. Hooley et al. Anal. Chem. 1983, 55, 313-320.
D. Betteridge et al, Anal. Chem, 1986, 58, 2258-2265.
K. W. Simonsen et al. J. Anal. Atom. Spectrom. 1986, 1, 453-456.
B. Xia et al. Youkuangye 1993, 12, 38-45.
O. Navratil et al. Anal Chim. Acta. 1970, 52, 221-227.
S. Shibata et al. Anal. Chim Acta 1976, 82, 169-174.
E. M. Sitnikova Chem. Abstr. 1976, 85, 201620f.
K. Yoshimura et al. Mem. Fac. Sci. Kyushu Univ., Ser. C 1979, 11, 181-188.
J. Ruzicka et al. Anal. Chim. Acta 1980, 114, 19-44.
J.L. Burguera et al. Anal. Chim Acta 1981, 127, 199-201.
L. Gorton et al. Anal. Chim. Acta 1981, 130, 45-53.
D.J. Hooley et al. Chem. Abstr. 1983, 98, 45998w.
D. Betteridge et al. Chem. Abstr. 1983, 99, 10931n.
S. S. Jorgensen et al. Anal. Chim. Acta 1985, 169, 51-57.
A. F. Kapauan et al. Anal. Chem. 1986, 58, 509-510.
K. W. Simonsen et al. Chem. Abstr. 1987, 106, 46716y.
A. M. Band et al. Anal. Chim. Acta 1987, 200, 213-225.
J. Ruz et al. Chem. Abstr. 1988, 108, 50755u.
C. Thommen et al. Ersenius Z. Anal. Chem. 1988, 329, 678-684.
H. K. Chung et al. Anal. Chem. 1990, 62, 2541-2547.
M. I. Nasir et al. Indian J. Chem. 1992, 31A, 285-287.
A. Katti et al. J. Chromatog. 1992, 590, 127-132.
T. Becker et al. J. Biotech. 1993, 31, 267-275.
B. Freire dos Reis et al. Analyst 1993, 118, 719-722.
B. Xia et al. Chem. Abstr. 1994 120, 234898x.
M. Jarosz, Chem. Anal., 1986, 31, 713-717.
E. R. Baggott, et al., Analyst, 1955, 80, 53-64.
S. Raptis, et al., Clin. Chim. Acta, 1978, 88, 393-402.
H. Chung-Gin, et al., Talanta, 1980, 27, 676-678.
H. Watanabe, et al., Talanta, 1979, 26, 959-961.
T. C. Chou et al., Chem. Abstr., 1981, 95, 180164z.
T. Hayashita et al., Bull. Chem. Soc. Jpn., 1990, 63, 576-580.
Y. Liu et al., Anal. Chem., 1989, 61, 520-524.
J.A.G. Neto et al., Anal. Chim. Acta, May 10, 1995, 306, 343-349.

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