Continuous fermentation process which is useful for the...

Details Continuous fermentation process which is useful for the... Continuous fermentation process which is useful for the...

2005-04-12

2005-04-12

Marx, Irene (Department: 1651)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing oxygen-containing organic compound

C435S119000, C435S170000

Reexamination Certificate

active

06878534

ABSTRACT:
The present invention relates to a fermentation process which is useful for the simultaneous production of propionic acid and vitamin B12, characterized in that it employs the culturing, on a suitable culture medium, of at least one microorganism suitable for the production of vitamin B12and propionic acid, and in that the corresponding fermentation is carried out in continuous fashion and involves at least two successive stages, a first stage associated with the optimal production of propionic acid, and a second with the optimal production of vitamin B12.

REFERENCES:
patent: 4794080 (1988-12-01), Mays
Menon et al., Arch. Biochem. Biophys. (1967), 121(2), 304-10.*
Stanbury et al., Principles of Fermentation Technology, Pergamon Press, 1984, p. 16-19.*
Rehm et al., “Biotechnology”. vol. 2, 1985, VCH, pp. 294-307.*
Kobayachi, T., Bioreactors Biotransformations, 1987, p. 158-165.*
Yougsmith et al., J. Ferment. Technol., vol. 61(6), 1983, p. 593-598.*
G. Belfort, “Fluid Mechanics in Membrane Filtration: Recent Developments,” Journal of Membrane Science, vol. 40, pp. 123-147 (1989).

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