Continuous blood gas monitoring

Internal-combustion engines – High tension ignition system – Safety device

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55158, 73 19, 7386323, 2103211, 436 68, 604 43, A61B 500

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active

045165807

ABSTRACT:
A method and apparatus for measuring of concentrations of components of a fluid mixture. One side of a membrane permeable to the component to be determined is contacted with a sample of the fluid mixture to be analyzed. The second side of the membrane is contacted with a test fluid passing the membrane at different speeds. The resultant properties of the test fluid are determined for the different speeds of flow past the membrane and the measured values allow to determine the concentration or partial pressure of the component in the fluid mixture. The fluid mixture is preferably blood and the components can be oxygen and carbon dioxide. Preferably the membrane provides a spiral path for the test fluid in order to allow employing a more rapid flow of the test fluid past the membrane. Furthermore, such a configuration can be combined with a catheter for hemodynamic blood pressure measurement thereby providing a single probe for continuous monitoring of blood in clinical practice.

REFERENCES:
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patent: 4235231 (1980-11-01), Schindler et al.
Massaro et al., "Non-Polorographic Blood Gas . . . ", Biomat, Med. Dev., Art. Org., 4 (3 and 4), 385-396, 1976.
Brantigan et al., "A Clinical Catheter . . . " J. App. Phys., vol. 40, No. 3, Mar. 1976, pp. 443-444.
Huchon et al., "Continuous Intravascular Monitoring . . . ", E. J. Intensive Care Med., vol. 2, 23-28, 1976.
Niinikoski et al., "Skeletal Muscle PO.sub.2 . . . " Adv. Exp. Med. Biol., vol. 94, pp. 582-586, 1977.
Clark et al., "A Self-Calibrating, . . . Monitor", Adv. Exp. Med. Biol., vol. 94, pp. 31-36, 1977.

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