Continuous and spontaneous interferon producing lymphoblastoid c

Details Continuous and spontaneous interferon producing lymphoblastoid c Continuous and spontaneous interferon producing lymphoblastoid c

1981-09-18

1984-09-04

Kepplinger, Esther M.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Enzymatic production of a protein or polypeptide

4351721, 4351723, 435240, 435811, 435948, C12P 2100, C12N 1500, C12N 500, C12R 191

Patent

active

044697902

ABSTRACT:
Process for preparing a continuous and spontaneous human-interferon-producing lymphoblastoid cell line which involves (a) transforming human lymphocytes isolated from a human infant from birth up to about 2 years or an aborted human fetus, the transforming being carried out with Epstein Barr Virus and (b) selecting from the resulting transformed cell lines a cell line producing more than 1000 units of interferon per milliliter when cultivated at a cell density of 10.sup.6 cells per milliliter in the absence of any interferon inducer.

REFERENCES:
patent: 3773924 (1973-11-01), Ho et al.
Friedman, Methods in Enzymology, vol. LVIII, Academic Press, New York, 292-296, (1979).
Steel et al., Nature, 270:729-730, (1977).
Pickering et al., PNAS USA, 77(10):5938-5942, (Oct. 1980).
Deinhart et al., J. Nat. Cancer Inst., 39:681-683, (1967).
Northrup et al., J. Nat. Cancer Inst., 39:685-689, (1967).
Kasel et al., Proc. Soc. Exp. Biol. Med., 128:351-353, (1968).
Zajac et al., Cancer Research, 29:1467-1475, (1969).
Haase et al., Proc. Soc. Exp. Biol. Med., 133:1076-1083, (1970).
Adams et al., J. Gen. Virol., 28:219-223, (1975).
Finter (Ed.), Interferon and Interferon Inducers, pp. 78, 80, 424 and 427, North-Holland Publ. Co., Amsterdam, Netherlands, (1973).
Chem. Abstracts, 89:21334n, (1978).
Chem. Abstracts, 92:126781y, (1980).

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