Continuous administration adenosine to increase myocardial blood

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

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536 276, A61K 3170, C07H 19167

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active

052310868

ABSTRACT:
This invention is concerned with the use of adenosine as an agent for the treatment of human beings. More particularly, this invention is concerned with the administration of adenosine to human patients by continuous intravenous infusion for, inter alia, control of blood pressure, use as a selective vasodilator, decreasing pulmonary vascular resistance, treating acute pulmonary hypertension in conjunction with idiopathic respiratory distress syndrome, in diagnosing pulmonary hypertension in conjunction with cardiac septum defects, in percutaneous transluminal angioplasty (PTCA), in coronary thrombolysis (CTL) and in radionucleide scintography.

REFERENCES:
patent: 4673563 (1987-06-01), Berne et al.
Fukunaga et al.(I), Anesthesia and Analgesia, 61, 273-278 (1982).
Fukunaga et al.(II), Anesthesiology, 57(3), A65 (1982).
Masters et al., Thorac. Cardiovasc. Surgeon, 30, 14-20 (1982).
Kassel et al., J. Neurosurg., 58, 69-76 (1983).
Sollevi et al., Acta Physiol. Scand., 120, 171-176 (1984).
Olsson et al., Circulation Research, 45(4), 468-478 (1979).

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