Container for injectable mesna solutions

Details Container for injectable mesna solutions Container for injectable mesna solutions

1997-08-21

1998-11-10

Criares, Theodore J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Sulfur, selenium or tellurium compound

A61K 31095

Patent

active

058345205

ABSTRACT:
Injectable mesna solutions having a pH value higher than 7.5. The solutions have increased storage stability.

REFERENCES:
patent: 4720379 (1988-01-01), Heyl et al.
Cerny et al., Bioavailability of subcutaneous Ifosfamide and feasibility of continuous outpatient application in cancer patients, Anals of Oncology, vol. I, pp. 365-368, 1990.
Kwon et al., "Activation Mechanisms of Mafosfamide and the Role of Thiols in Cyclophosphamide Metabolism", J.Med.Chem. 1987, vol. 30, pp. 395-399.
Leeuwenkamp, et al., Reaction Kinetics of Cisplatin and its Monoaquated Species with the Modulating Agents (Di)mesna and Thiosulphate, Eur.J.Cancer, vol. 27, No. 10, pp. 1243-1247, 1991.
Rote Liste 1992.

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