Container, apparatus and method for separating platelets

Chemistry: physical processes

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233 26, 210 961, 210787, 210927, 422 44, 23913, 220 205, B04B 1102, B04B 300

Patent

active

043445608

ABSTRACT:
A container for the continuous centrifugal separation of platelets component in blood, having a first and a second closed chambers adaptable to be rotated around a rotation axis. Whole blood is continuously introduced into the first chamber. Platelet-rich plasma being obtained as supernatant in the first chamber being discharged through a first outlet port opened at a relatively short distance from the rotation axis and being then introduced into the second chamber. Precipitation in the first chamber being discharged through a second outlet port opened at a relatively long distance from the rotation axis. The consistency of the blood in the first chamber being monitored at a predetermined position which differs from the opened position of the first outlet port and being located between the opened positions of the first and second outlet ports with respect to the distance from the rotation axis. The quantity of the discharge flow through at least one of the first and second outlet ports being controlled so that the consistency of blood maintain a certain constant value. Supernatant in the second chamber is discharged through a third outlet port opened to the second chamber. Platelets component in a high purity content is obtained as precipitation in the second chamber.

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patent: 4091989 (1978-05-01), Schlutz
patent: 4114802 (1978-09-01), Brown
patent: 4284602 (1981-08-01), Kelton et al.

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