Contact lens of hydrophilic gels with inhibitor and swelling age

Details Contact lens of hydrophilic gels with inhibitor and swelling age Contact lens of hydrophilic gels with inhibitor and swelling age

1995-01-09

1997-03-04

Levy, Neil S.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

523106, 514839, A61K 900

Patent

active

056076886

ABSTRACT:
The contact lens made of hydrophilic gels contains substantially 20 to 65 percent by weight of a swelling agent in the equilibrium swollen state. An example of the swelling agent can be physiological saline, water, or buffer with pH 6.5 to 7.5. The lens contains inhibitors of endoproteases and exoproteases such as aprotinin, elastatinal, and soybean. The lens may also include some type of steroidal and/or nonsteroidal antiphlogistics. The lens may also contain antibiotics. The contact lens is used for longer term wearing and may also be used for the treatment of various lesions of the anterior eye segment.

REFERENCES:
patent: 4703108 (1987-10-01), Silver et al.
patent: 4931279 (1990-06-01), Bawa et al.
patent: 4939135 (1990-07-01), Robertson et al.
patent: 5202118 (1993-04-01), Gillis et al.
USPDI--1989 pp. 2449/1356 Indomethnacin.
USP 1989 Nineth edition, pp. 2449; 1356.

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