Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert
Reexamination Certificate
2007-09-04
2011-12-13
Azpuru, Carlos (Department: 1617)
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Implant or insert
Reexamination Certificate
active
08075909
ABSTRACT:
A bioactive agent delivery system comprising an optically transparent contact lens having dispersed therein (1) an ophthalmically bioactive agent capable of diffusion through the contact lens and into the post-lens tear film when placed on the eye and (2) associated with the bioactive agent, an ophthalmically compatible polymeric surfactant in an amount sufficient to slow the rate of migration of the bioactive agent through the contact lens.
REFERENCES:
patent: 5034461 (1991-07-01), Lai et al.
patent: 5410016 (1995-04-01), Hubbell et al.
patent: 5412072 (1995-05-01), Sakarai et al.
patent: 5449513 (1995-09-01), Yokoyama et al.
patent: 5496871 (1996-03-01), Lai et al.
patent: 5610252 (1997-03-01), Bambury et al.
patent: 5693751 (1997-12-01), Sakurai et al.
patent: 5723131 (1998-03-01), Schultz et al.
patent: 5925720 (1999-07-01), Kataoka et al.
patent: 5929177 (1999-07-01), Kataoka et al.
patent: 6410045 (2002-06-01), Schultz
patent: 7037517 (2006-05-01), Kataoka et al.
patent: 7674478 (2010-03-01), Kataoka et al.
patent: 2004/0120982 (2004-06-01), Diana et al.
patent: 2004/0241207 (2004-12-01), Chauhan et al.
patent: 2006/0177483 (2006-08-01), Byrne et al.
patent: 2006/0246113 (2006-11-01), Griffith et al.
patent: WO 96/32434 (1996-10-01), None
patent: WO 96/33233 (1996-10-01), None
patent: WO 97/00623 (1997-01-01), None
International Search Report dated Apr. 21, 2009 in corresponding application PCT/US2008/010353.
Written Opinion of the International Searching Authority in corresponding application PCT/US2008/010353 dated Apr. 21, 2009.
Rodriguez R, Alvarez-Lorenzo C, Concheiro A, “Influence of cationic cellulose structure on its interactions with sodium dodecylsulfate: implications on the properties of the aqueous dispersions and hydrogels”, European Journal of Pharmaceutics and Biopharmaceutics 56 (1): 133-142 2003.
Barreiro-Iglesias R, Alvarez-Lorenzo C, Concheiro A, “Thermal and FTIR characterization of films obtained from carbopol/surfactant aqueous solutions”, Journal of Thermal Analysis and Calorimetry, 68 (2): 479-488 2002, 2005.
Barreiro-Iglesias R, Alvarez-Lorenzo C, Concheiro A, “Incorporation of small quantities of surfactants as a way to improve the rheological and diffusional behavior of carbopol gels”, Journal of Controlled Release, 77 (1-2): 59-75, 2001.
Paulsson M, Edsman K, “Controlled drug release from gels using lipophilic interactions of charged substances with surfactants and polymers”, Journal of Colloid and Interface Science, 248 (1): 194-200, 2002.
Paulsson M, Edsman K, “Controlled drug release from gels using surfactant aggregates. II. Vesicles formed from mixtures of amphiphilic drugs and oppositely charged surfactants”, Pharmaceutical Research, 18 (11): 1586-1592, 2001, Colloids and Surfaces B-Biointerfaces, 46 (3): 142-146.
Paulsson M, Edsman K, “Controlled drug release from gels using surfactant aggregates: I. Effect of lipophilic interactions for a series of uncharged substances”, Journal of Pharmaceutical Sciences, 90 (9): 1216-1225, 2001.
Mandell, R.B., “Contact Lens Practice: Hard and Flexible Lenses” , 2nd ed., Charles C. Thomas, Springfield, vol. 3, 1974.
Creech, J.L., Chauhan, A., Radke, C.J., “Dispersive mixing in the posterior tear film under a soft contact lens”, I&EC Research, 2001, 40: 3015-3026.
McNamara, N.A., Polse, K.A., Brand, R.D., Graham, A.D., Chan, J.S., McKenney, C.D., “Tear mixing under a soft contact lens: Effects of lens diameter”. Am. J. of Ophth., 1999, 127(6): 659-65].
Nagarsenker, M.S., Londhe, V.Y., Nadkarni, G.D., “Preparation and evaluation of liposomal formulations of tropicamide for ocular delivery”, Int. J. of Pharm., 1990, 190: 63-71.
Lang, J.C., “Ocular drug delivery conventional ocular formulations”. Adv. Drug Delivery, 1995, 16: 39-43.
Bourlais, C.L., Acar, L., Zia H., Sado, P.A., Needham, T., Leverge, R., “Ophthalmic drug delivery systems”, Progress in retinal and eye research, 1998, 17, 1: 33-58.
Segal, M., “Patches, pumps and timed release”, FDAConsumermagazine, Oct. 1991.
Hehl, E.M., Beck, R., Luthard K., Guthoff R., “Improved penetration of aminoglycosides and fluoroquinolones into the aqueous humour of patients by means of Acuvue contact lenses”, European Journal of Clinical Pharmacology, 1999, 55 (4): 317-323.
Hillman, J. S., “Management of acute glaucoma with Pilocarpine-soaked hydrophilic lens” Brit. J. Ophthal.58 (1974) p. 674-679.
Ramer, R. and Gasset, A., “Ocular Penetration of Pilocarpine:” Ann.Ophthalmol.6, (1974) p. 1325-1327.
Montague, R. and Wakins, R., “Pilocarpine dispensation for the soft hydrophilic contact lens” Brit .J. Ophthal. 59, (1975) p. 455-458.
Hillman, J.,Masters, J. and Broad, A. “Pilocarpine delivery by hydrophilic lens in the management of acute glaucoma” Trans. Ophthal. Soc.U. K. (1975) p. 79-84.
Giambattista, B.,Virno, M., Pecori-Giraldi, Pellegrino, N. and Motolese, E. “Possibility of Isoproterenol Therapy with Soft Contact Lenses: Ocular Hypotension Without Systemic Effects” Ann. Ophthalmol 8 (1976) p. 819-829.
Marmion, V. J. and Yardakul, S. “Pilocarpine administration by contact lens” Trans. Ophthal. Soc.U. K. 97, (1977) p. 162-163.
Hiratani H, Alvarez-Lorenzo C—“The nature of backbone monomers determines the performance of imprinted soft contact lenses as timolol drug delivery systems” Biomaterials 25,1105-1113, 2004.
Hiratani H, Fujiwara A, Tamiya Y, Mizutani Y, Alvarez-Lorenzo C—“Ocular release of timolol from molecularly imprinted soft contact lenses” Biomaterials 26,1293-1298, 2005.
Hiratani H, Mizutani Y, Alvarez-Lorenzo C—“Controlling drug release from imprinted hydrogels by modifying the characteristics of the imprinted cavities” Macromol Biosci 5,728-733, 2005.
Alverez-Lorenzo C, Hiratani H, Gomez-Amoza JL, Martinez-Pacheco R, Souto C, Concheiro A—“Soft contact lenses capable of sustained delivery of timolol” J Pharm Sci 91,2182-2192, 2002.
Hiratani H, Alvarez-Lorenzo C—“Timolol uptake and release by imprinted soft contact lenses made of N,N-diethylacrylamide and methacrylic acid” J Control Release 83,223-230, 2002].
Elisseeff, J., McIntosh, W., Anseth, K., Riley, S., Ragan, P., Langer, R., “Photoencapsulation of chondrocytes in poly(ethylene oxide)-based semi-interpenetrating networks”, Journal of Biomedical Materials Research, 2000, 51 (2): 164-171.
Ward, J. H., Peppas, N. A., “Preparation of controlled release systems by free-radical UV polymerizations in the presence of a drug”, Journal of Controlled Release, 2001, 71 (2): 183-192.
Scott, R. A., Peppas, N. A., “Highly crosslinked, PEG-containing copolymers for sustained solute delivery”, Biomaterials, 1999, 20 (15): 1371-1380.
Podual, K., Doyle F. J., Peppas N. A., “Preparation and dynamic response of cationic copolymer hydrogels containing glucose oxidase”, Polymer, 2000, 41 (11): 3975-3983.
Colombo, P., Bettini, R., Peppas, N.A., “Observation of swelling process and diffusion front position during swelling in hydroxypropyl methyl cellulose(HPMC)matrices containing a soluble drug”, Journal of Controlled Release, 1999, 61 (1,2): 83-91.
Ende, M.T.A., Peppas, N.A., “Transport of ionizable drugs and proteins in crosslinked poly(acrylic acid)and poly(acrylic acid-co-2-hydroxyethyl methacrylate)hydrogels. 2. Diffusion and release studies”, Journal of Controlled Release, 1997, 48 (1): 47-56.
Gulsen D, Chauhan A—“Dispersion of microemulsion drops in HEMA hydrogel: a potential ophthalmic drug delivery vehicle”. Int J Pharm 292,95-117, 2005.
Gulsen D, Chauhan A—“Ophthalmic drug delivery through contact lenses”. Invest Ophth Vis Sci 45,2342-2347, 2004.
Graziacascone, M., Zhu, Z., Borselli, F., Lazzeri, L., &#
Chauhan Anuj
Kapoor Yash
Azpuru Carlos
Miles & Stockbridge P.C.
Schafter, Esq. David R.
University of Florida Research Foundation Incorporated
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