Construction of Pasteurella haemolytica vaccines

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4351723, 4353201, C12N 1574, C12N 1500

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057337802

ABSTRACT:
Methylation of DNA can be a critical step in the introduction of DNA into P. haemolytica. A methyltransferase has been isolated and molecularly cloned for this purpose. Use of the methyltransferase has allowed construction of defined, attenuated mutants for use as vaccines to protect cattle.

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