Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound containing saccharide radical
Reexamination Certificate
2011-02-08
2011-02-08
Ketter, James S (Department: 1636)
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing compound containing saccharide radical
C435S098000, C435S164000, C435S165000, C536S023200, C536S023740
Reexamination Certificate
active
07883872
ABSTRACT:
This invention provides novel enzyme compositions using newly identified and isolatedC. lucknowenseenzymes, including CBH Ib CBH IIb, EG II, EG VI, β-glucosidase, and xylanase II in conjunction with previously identified enzymes CBH Ia, CBH IIa (previously described as Endo 43), and EG V. These enzyme compositions demonstrate an extremely high ability to convert lignocellulosic biomass (e.g., Avicel, cotton, Douglas fir wood pretreated by organosolv) to glucose. CBH Ia and IIb, which both have a cellulose-binding module (CBM) displayed a pronounced synergism with three major endoglucanases (EG II, EG V, EG VI) from the same fungus in hydrolysis of cotton as well as a strong synergy with each other. The enzyme compositions are effective in hydrolysis of the lignocellulosic biomass.
REFERENCES:
Agency Response Letter GRAS Notice No. GRN 000292 (Sep. 29, 2009) from Mitchell A. Cheeseman, Acting Director; hyper text transfer protocol://www.fda.gov.
Antonov Alexey I.
Baez Marco A.
Burlingame Richard P.
Emalfarb Mark A.
Gusakov Alexander V.
Dyadic International (USA), Inc.
Keller Michael J.
Ketter James S
McDermott Will & Emery LLP
Sullivan Nicole R.
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