Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Reexamination Certificate
2011-01-04
2011-01-04
Popa, Ileana (Department: 1633)
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
C435S410000, C800S279000
Reexamination Certificate
active
07863430
ABSTRACT:
The present invention relates generally to constructs and in particular genetic constructs comprising polynucleotide sequences capable of release in covalently closed, circular form from a larger nucleotide sequence such as a genome of a eukaryotic cell. Preferably, once released, a polynucleotide sequence is reconstituted in a form which permits expression of the polynucleotide sequence. In one embodiment, the reconstituted polynucleotide sequence comprises a coding sequence with all or part of an extraneous nucleotide such as an intronic sequence or other splice signal inserted therein. Expression and in particular transcription of the coding sequence involves splicing out the extraneous sequence. The release and circularization is generally in response to a stimulus such as a protein-mediated stimulus. More particularly, the protein is a viral or prokaryotic or eukaryotic derived protein or developmentally and/or tissue specific regulated protein.
REFERENCES:
patent: 6077992 (2000-06-01), Yadav
patent: WO 00/17365 (2000-03-01), None
Liu et al., Journal of General Virology, 1999, 80: 501-506.
Ryan et al., J Virol, 1996, 70: 1542-1553, Abstract.
Wu et al., Archives of Biochemistry, 2001, 389: 271-277.
Im et al., J Virol, 1989, 63: 3095-3104, Abstract.
Laufs et al., Biochimie, 1995, 77: 765-773.
Behjatnia et al., Nucleic Acids Research, 1998, 26: 925-931.
Mourgues et al., Trends Biotechnol, 1998, 16: 203-210.
GenBank accession No. M81103.
Atkinson, R. G., et al., “Post-Transcriptional Silencing of Chalcone Synthase in Petunia Using a Geminivirus-Based Episomal Vector,”The Plant Journal, 1998, pp. 593-604, vol. 15 (5).
Kilby, N. J., et al., “Site-Specific Recombinases: Tools for Genome Engineering,”TIG, 1993, pp. 413-421, vol. 9 (12).
Lazarowitz, S. G., “Geminiviruses: Genome Structure and Gene Function,”Critical Reviews in Plant Sciences, 1992, pp. 327-349, vol. 11 (4).
Needham, P. D., et al., “GUS Expression Patterns from a Tobacco Yellow Dwarf Virus-Based Episomal Vector,”Plant Cell Reports, 1998, pp. 631-639, vol. 17.
Onouchi, H., et al., “Operation of an Efficient Site-Specific Recombination System ofZygosaccharomyces rouxiiin Tobacco Cells,”Nucleic Acids Research, 1991, pp. 6373-6378, vol. 19 (23).
Palmer, K. E., and E. P Rybicki, “The Molecular Biology of Mastreviruses,”Advances in Virus Research, 1998, pp. 183-234, vol. 50.
Satoh, W., et al., “Site Specific Integration of an Adeno-Associated Virus Vector Plasmid Mediated by Regulated Expression of Rep based on Cre-loxPrecombination.” Journal of Virology, Nov. 2000, pp. 10631-10638, vol. 74 No. 22, American Society for Microbiology.
Hafner, G. J., et al., “Nicking and Joining Activity of Banana Bunchy Top Virus Replication Protein in vitro,” Journal of General Virology, 1997, pp. 1795-1799, vol. 78, Great Britain.
International Search Report from corresponding International Application PCT/AU01/00349 dated May 24, 2001.
Becker Douglas Kenneth
Chowpongpang Srimek
Dale James Langham
Dugdale Benjamin
Hafner Greg John
Alston & Bird LLP
Popa Ileana
Queensland University of Technology
LandOfFree
Construct capable of release in closed circular form from a... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Construct capable of release in closed circular form from a..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Construct capable of release in closed circular form from a... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2671418