Drug – bio-affecting and body treating compositions – Identification or warning feature – Taste or smell or chemical irritation to the eye – nose – or...
Patent
1983-01-03
1984-07-24
Rose, Shep K.
Drug, bio-affecting and body treating compositions
Identification or warning feature
Taste or smell or chemical irritation to the eye, nose, or...
424 22, 424 35, A61K 922, A61K 926
Patent
active
044617593
ABSTRACT:
A constant order release rate solid oral dosage formulation of verapamil or a pharmaceutically acceptable salt thereof, said formulation comprising: a therapeutically effective amount of verapamil; from about 0.5 to 6.0 weight percent of an acid-retardant or hydrophobic cellulose derivative; from about 2.5 to 35 weight percent of a hydrogenated vegetable oil: from about 1 to 20 weight percent of an acrylic acid polymer; from about 0.5 to 4.0 weight percent of fumed silicon dioxide and from about 0.4 to 3.0 percent of a lubricant.
REFERENCES:
patent: 3577514 (1971-05-01), Robinson
Gibson et al., CA.97 #133454a(1982).
Juslin et al., CA.96 #40847v(1982).
Khanna et al., CA.94 #127301v(1981).
Jayaswal et al., CA.93 #155800e(1980).
Chasseaud et al., CA.85 #68210d(1976).
Ekenved et al., CA.76 #1037562(1972).
Rose Shep K.
Verex Laboratories, Inc.
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