Drug – bio-affecting and body treating compositions – Identification or warning feature – Taste or smell or chemical irritation to the eye – nose – or...
Patent
1984-02-17
1985-06-04
Rose, Shep K.
Drug, bio-affecting and body treating compositions
Identification or warning feature
Taste or smell or chemical irritation to the eye, nose, or...
424 22, A61K 922, A61K 926
Patent
active
045214026
ABSTRACT:
A constant order release rate solid oral dosage formulation of hydralazine or a pharmaceutically acceptable salt thereof, said formulation comprising: a therapeutically effective amount of hydralazine or a pharmaceutically acceptable salt; from about 0.5 to 6.0 weight percent of an acid-retardant or hydrophobic cellulose derivative; from about 2.5 to 35 weight percent of a hydrogenated vegetable oil: from about 1 to 20 weight percent of an acrylic acid polymer; from about 0.5 to 4.0 weight percent of fumed silicon dioxide and from about 0.4 to 3.0 percent of a lubricant.
REFERENCES:
patent: 3400197 (1968-09-01), Lippmann
patent: 4248856 (1981-02-01), Guley et al.
patent: 4248857 (1981-02-01), DeNeale et al.
patent: 4248858 (1981-02-01), Guley et al.
Liedholm et al., C.A. 98, #78050j, (1983).
Hisosaka et al., C.A. 96, #205433x, (1982).
Talseth et al., C.A. 86, #195134c, (1977).
Rose Shep K.
Verex Laboratories, Inc.
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