Constant order release, solid dosage indomethacin formulation an

Details Constant order release, solid dosage indomethacin formulation an Constant order release, solid dosage indomethacin formulation an

1984-08-06

1985-06-25

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Solid synthetic organic polymer as designated organic active...

Polymer from ethylenic monomers only

424 19, 424 35, A61K 922, A61K 930, A61K 952, A61K 956

Patent

active

045253455

ABSTRACT:
A constant release rate indomethacin formulation in tablet unit dosage form, said tablet comprising an intimate admixture of from 50 to 200 mg of indomethacin, from about 1.7 to 3.7 weight percent of a slow-dissolving, water-insoluble cellulose derivative, from about 1.5 to 5.0 weight percent of a tabletting disintegrant, and from about 40 to 80 weight percent of a pharmaceutically acceptable bulking agent or diluent.

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Chiyoda Yakuhin C.A. 100 #12691x (1984) of JPN 58-170, 712, 07 Oct. 1983, Sustained-Release Indomethacin Tablets.
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Panoz et al, C.A. 95 #12/166d (1981) of PCT Int. Appl. 81-01,6520, 07 Dec. 1979, Galenical Preparation with Delayed Action and Programmed Release.
Dittgen et al, C.A. 89 #120878G (1978) Pharmazie 1977, 32(12) 771-7 Drug Release from Embedding Forms based on Polycacrylate.
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Morse C.A. 74 #67738T (1971) of U.S. 3 557 279, 19 Jan. 1971, Microencapsulation Form of Anti-Inflammatory Indomethacin.

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