Chemistry: physical processes – Physical processes – Crystallization
Patent
1975-06-25
1976-01-20
Serwin, R. E.
Chemistry: physical processes
Physical processes
Crystallization
23230M, 23230B, 23253R, 73 611C, G01N 3108, G01N 2126
Patent
active
039334309
ABSTRACT:
A method and apparatus for the detection of primary and secondary amino acids in a known sequence in a liquid sample stream. The amino acids are rendered detectable by reaction with a fluorometric reagent such as fluorescamine. A conversion reagent, e.g., N-chlorosuccinimide, is added to the sample streams only when secondary amine is present. Baseline shift in the fluorometric detection is avoided by adding an inert liquid diluent stream to the sample stream at a predetermined flow rate at all times except when the conversion reagent is added. By maintaining the diluent and N-chlorosuccinimide streams under constant pressure and synchronously switching between streams to coincide with the presence of a primary or secondary amino acid, liquid flow through the fluorometer is maintained at a substantially constant rate throughout the run.
REFERENCES:
patent: 3484170 (1969-12-01), Smythe et al.
patent: 3551107 (1970-12-01), Hrdina
eveleigh et al., "An Automated Amino Acid Analysis System," Technicon Symposia, 1967, Vol. I, pp. 311-319.
St. John, "New Method for Probine and Hydroxyproline Extends Usefulness of Fluorometric Amino Acid Analysis," Aminco Lab. News Vol. 31, No. 1, Spring 1975, pp. 1 & 2.
Durrum Instrument Corporation
Serwin R. E.
LandOfFree
Constant flow system for detection of amino acids does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Constant flow system for detection of amino acids, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Constant flow system for detection of amino acids will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1693787